In vivo Research

Non-Regulatory / Efficacy Studies

In Vivo Services

Cardiovascular Pharmacology

• Anti-hypertensive Activity
  
  • DOCA – High Salt induced Hypertension
    
  • 2K/1C Renal Hypertension
    
  • Abdominal Aortic banding induced hypertension
    
• Isoproterenol Induced Myocardial Necrosis
  
• Diuretic Activity
  

Metabolic Disorder Pharmacology

• Diabetes Model: STZ or High Fat Diet
  
• Anti-Obesity Activity
  
• Antherosclerosis – Cholesterol Diet Induced
  
• Titron induced Hyperlipidemia
  

Xenograft Tumour Model

Anti-cancer model

Xenograft

• e.g.U87MG – Human Glioblastoma Cell lines induced Antiglioma
• HCT – 15 Induced Colon Cancer
• MCF7 Induced Breast Cancer
  

Orthotropic

• USC HM3-GFP induced HNSCC
  

Neuropharmacology

• ALS ( Amyotrophic Lateral Sclerosis)
  
• Scopolamine Induced Dementia
  
• MPTP induced Parkinsonism – Acute and chronic Model
  
• Stroke – Middle Cerebral Artery Occlusion and Reperfusion
  

Neuro-Behavioural Test

• Maxes ( Y Maxe, Plus Maze, Radial Maze)
  
• Open Field Test
  
• Beam Walk
  
• Rota rod
  

Inflammatory Pharmacology

• Wound Healing Models
  
• Carragenanan Induced Paw Edema
• Collagenase Induced Tendonitis
• Formalin Test
  
• MIA induced Arthrities
  
• Adjuvant Induced Arthritis
  

Infection Models (BSL-II)

• MRSA induced Thigh Infection
  
• C.Albicans Induced Systemic Infection
• E.Coli induced Thigh Infection

Please contact us to discuss your project needs.